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Accession: PRJNA521411 ID: 521411

Single-cell combinatorial indexing ATAC-seq of HCC1143 with MEK, PI3K, and BET inhibition (human)

See Genome Information for Homo sapiens
We performed single-cell combinatorial indexing ATAC-seq on the basal-like TNBC cell line HCC1143 under MEK, PI3K, BET and combination treatments as well as DMSO controls Overall design: Cells were cultured and exposed to inhibitors or vehicle for 72 hours and processed in a single batch of sci-ATAC-seq using transposition barcodes for sample tracking to eliminate batch effects downstream
AccessionPRJNA521411; GEO: GSE126261
Data TypeTranscriptome or Gene expression
ScopeMonoisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsRisom T et al., "Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer.", Nat Commun, 2018 Sep 19;9(1):3815
SubmissionRegistration date: 7-Feb-2019
Adey Lab, MMG, Oregon Health & Science University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments1
Publications
PubMed1
PMC1
Other datasets
BioSample1
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes9
SRA Data Details
ParameterValue
Data volume, Gbases12
Data volume, Mbytes4553

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