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Accession: PRJNA521260 ID: 521260

Mismatch-repair signature mutations activate gene enhancers across human colorectal cancer epigenomes (human)

See Genome Information for Homo sapiens
We show that mismatch-repair (MMR) signature mutations can activate colorectal cancer (CRC)-specific enhancers, through analysis of enhancer DNA associated with the active enhancer histone mark H3K27ac. More...
AccessionPRJNA521260; GEO: GSE126188
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsHung S et al., "Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes.", Elife, 2019 Feb 13;8
SubmissionRegistration date: 6-Feb-2019
Case Western Reserve University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments13
Publications
PubMed1
PMC1
Other datasets
BioSample13
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1452
SRA Data Details
ParameterValue
Data volume, Gbases59
Data volume, Mbytes24957

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