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6 additional projects are components of the CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation.
In this study we identified genes regulated by CASZ1b in SMS-CTR cells
Overall design: In the CASZ1b stably transfected SMS-CTR cells (CTRtetCASZ1b), CASZ1b expression is Doxcycline (Dox) inducible . RNA was isolated from CTRtetCASZ1b cells that treated with or without Dox for 48 hr
| Accession | PRJNA521143; GEO: GSE126145 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Liu Z et al., "CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.", Nat Commun, 2020 Feb 14;11(1):911 |
| Submission | Registration date: 6-Feb-2019
POB, NCI |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 10 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 10 |
| GEO DataSets | 1 |