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6 additional projects are components of the CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation.
In this study we identified genes regulated by CASZ1b in C2C12 cells
Overall design: 1) RNA was isolated from C2C12 cells that transfected with empty vector (EV), CASZ1a or CASZ1b and cultured in regular growth medium for 48 hr; 2) RNA was isolated from C2C12 cells that stably transfected with shCtrl or shCasz1 and cultured in differentiation medium for 48 hr.
| Accession | PRJNA521142; GEO: GSE126144 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Liu Z et al., "CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.", Nat Commun, 2020 Feb 14;11(1):911 |
| Submission | Registration date: 6-Feb-2019
POB, NCI |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 15 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 15 |
| GEO DataSets | 1 |