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Accession: PRJNA520888 ID: 520888

Deletion of the KH1 domain coding sequence of Fmr1 leads to transcriptional alterations and attentional deficits in rats (Norway rat)

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We found that the previously published Fmr1 knockout rat model of FXS expresses an Fmr1 transcript with an in-frame deletion of exon 8, which encodes for the K-homology (KH) RNA-binding domain, KH1. More...
AccessionPRJNA520888; GEO: GSE126057
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismRattus norvegicus[Taxonomy ID: 10116]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus
PublicationsGolden CEM et al., "Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats.", Cereb Cortex, 2019 May 1;29(5):2228-2244
SubmissionRegistration date: 4-Feb-2019
Depts. of Psychiatry, Genetics and Genomic Sciences, Ichan School of Medicine at Mount Sinai
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments45
Publications
PubMed1
PMC1
Other datasets
BioSample45
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes14
SRA Data Details
ParameterValue
Data volume, Gbases380
Data volume, Tbytes0.23

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