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3 additional projects are components of the Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation.
Purpose: Study the changes in cell transcriptome upon overexpression of lncRNA TINCR
Methods: Primary melanoma cell line WM902B was transduced with lientiviruses expressing Scrambled and TINCR directed shRNA hairpins
Results: we found that TINCR overexpression induces partial reversion of invasive phenotype
Overall design: Analysis of differential gene expression in control and TINCR overexpressing MM2 and MM13 metastsatic melanoma PDX cells
| Accession | PRJNA517676; GEO: GSE125834 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Melixetian M et al., "Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation.", EMBO Rep, 2021 Mar 3;22(3):e50852 |
| Submission | Registration date: 29-Jan-2019
European Institute of Oncology |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 8 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 8 |
| GEO DataSets | 1 |