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Accession: PRJNA517459 ID: 517459

p53-inducible long non-coding RNAs encode functional peptides in hepatocellular carcinoma cells [RNA-seq] (human)

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This project is a component of the p53-inducible long non-coding RNAs encode functional peptides in hepatocellular carcinoma cells
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1 additional project is a component of the p53-inducible long non-coding RNAs encode functional peptides in hepatocellular carcinoma cells.
66644 additional projects are related by organism.
To identify p53-regulated lncRNAs responsive to DNA damage in human hepatocellular carcinoma (HCC) cells, we conducted paired-end and strand-specific RNA-seq using HepG2 wild-type and p53-knockout (HepG2-KO-p53) cells, which were devoid of p53 protein, using the CRISPR-Cas9 system treated with or without the DNA-damaging agent adriamycin (ADR) Overall design: RNA-seq profiles of HepG2 p53 wild-type (WT) and HepG2 p53 knockout (p53−/−) treated with ADR or not were generated by deep sequencing, in two independent experiments, using Illumina Xten. More...
AccessionPRJNA517459; GEO: GSE125756
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 28-Jan-2019
School of Life Sciences, Sun Yat-sen University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes5
SRA Data Details
ParameterValue
Data volume, Gbases112
Data volume, Mbytes48092

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