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Accession: PRJNA517447 ID: 517447

Whole transcriptome sequencing of mESCs (house mouse)

See Genome Information for Mus musculus
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This project is a component of the PRDM15 loss-of-function causes brain malformations through defective embryonic anterior-posterior patterning
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3 additional projects are components of the PRDM15 loss-of-function causes brain malformations through defective embryonic anterior-posterior patterning.
47588 additional projects are related by organism.
Investigation of the ability of WT or mutant hPRDM15 to restore the transcriptional changes induced by deletion of the endogenous mouse Prdm15 Overall design: OHT (50nM) was added to the medium O/N to delete endogenous mouse Prdm15 from isogenic Prdm15flf::RCM2. More...
AccessionPRJNA517447; GEO: GSE125749
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsMzoughi S et al., "PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.", Sci Adv, 2020 Jan;6(2):eaax9852
SubmissionRegistration date: 28-Jan-2019
Chromatin, Epigenetics & Differentiation, Institute of Molecular and Cell Biology
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases49
Data volume, Mbytes20742

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