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Accession: PRJNA517418 ID: 517418

DNA hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo DCs [hMeDIP-seq] (water buffalo)

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This project is a component of the DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo DCs
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1 additional project is a component of the DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo DCs.
67 additional projects are related by organism.
Purpose: To investigate whether FgESP affects the hydroxylmethylation level of DCs Methods: we have profiled the DNA hydroxymethylome by using hydroxymethylated DNA immunoprecipitation sequencing (h)MeDIP-Seq in the current study Results: DNA hydroxymethylation profiles revealed significant changes in the 5-hydroxymethylcytosine (5hmC) levels in 360 genes when DCs were treated with FgESPs. More...
AccessionPRJNA517418; GEO: GSE125735
Data TypeEpigenomics
ScopeMultiisolate
OrganismBubalus bubalis[Taxonomy ID: 89462]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus; Bubalus bubalis
PublicationsMei XF et al., "DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo dendritic cells.", Parasit Vectors, 2019 Jul 23;12(1):358
SubmissionRegistration date: 28-Jan-2019
College of Animal Science and Technology, Guangxi University
RelevanceAgricultural
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments8
Publications
PubMed1
PMC1
Other datasets
BioSample8
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes11
SRA Data Details
ParameterValue
Data volume, Gbases60
Data volume, Mbytes27275

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