See
Genome Information for Homo sapiens
Genome-wide association studies of tumor samples have identified a large number of lncRNAs associated with various types of cancer including colorectal cancer. To elucidate the mechanism by which CASC9 regulates colorectal cancer cell growth, RNA-sequencing was performed to analyze the gene expression profile affected by CASC9 knockdown. A total of 249 significantly upregulated genes and 491 significantly downregulated genes (absolute fold change ≥ 2, P < 0.05) were found in CASC9 knockdown HCT-116 cells.
Overall design: Comparing gene expression profiles of HCT-116 cells transfected with CASC9 GapmeR (GapC9) and the control GapmeR (GapNC)
| Accession | PRJNA517086; GEO: GSE125648 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Luo K et al., "LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.", J Exp Clin Cancer Res, 2019 Jun 11;38(1):249 |
| Submission | Registration date: 25-Jan-2019
Wenzhou Medical University |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 1 |