RNA-sequencing of human mammary epithelial cells (... (ID 517072) - BioProject

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Accession: PRJNA517072 ID: 517072

RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation (human)

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3 additional projects are components of the The interplay between SOX4 and SMAD3 in the context of breast cancer.

Through RNA-sequencing we analysed the differentially expressed genes upon inducible activation of SOX4. More...

Accession	PRJNA517072; GEO: GSE125642
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Vervoort SJ et al., "SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.", Nucleic Acids Res, 2018 Oct 12;46(18):9578-9590 Vervoort SJ et al., "Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis.", Elife, 2018 Dec 3;7
Submission	Registration date: 25-Jan-2019 UMC Utrecht
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	3

Parameter	Value
Data volume, Gbases	9
Data volume, Mbytes	4131

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RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express e...
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation
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