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Accession: PRJNA516830 ID: 516830

Expression data (A2058) after treatment with MAPKi, HDACi or both (human)

See Genome Information for Homo sapiens
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This project is a component of the Expression data of 3 melanoma cell lines after treatment with MAPKi, HDACi or both
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2 additional projects are components of the Expression data of 3 melanoma cell lines after treatment with MAPKi, HDACi or both.
66644 additional projects are related by organism.
Transcriptional profiles were examined in A2058 melanoma cells treated with vehicle (DMSO), dabrafenib+trametinib (DT, MAPKi), entinostat (E, HDACi) or all 3 agents (DTE) at 24 hours, prior to the commencement of cell death, to investigate the molecular mechamism by which these drugs and their combinations are functioning. More...
AccessionPRJNA516830; GEO: GSE125560
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 24-Jan-2019
Karen Cichowski, Genetics, Brigham and Women's Hospital
RelevanceMedical
Project Data:
Resource NameNumber
of Links
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots352752
Data volume, Processed Mbytes8
Data volume, Supplementary Mbytes94

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