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Accession: PRJNA516454 ID: 516454

The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA516454; GEO: GSE125475
TypeUmbrella project
PublicationsGentili M et al., "The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.", Cell Rep, 2019 Feb 26;26(9):2377-2393.e13
SubmissionRegistration date: 22-Jan-2019
INSERM U932, Institut Curie
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes358
SRA Data Details
ParameterValue
Data volume, Gbases142
Data volume, Mbytes73947
The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus encompasses the following 2 sub-projects:
Project TypeNumber of Projects
Epigenomics2
BioProject
accession
OrganismTitle
PRJNA516357Homo sapiensNuclear GFP ChIP-seq from human Monocyte Derived Dendritic Cells transduced with GFP-NLS-cGAS or GFP-NLS (INSERM U932, Institut Curie)
PRJNA516356Mus musculusNuclear GFP ChIP-seq from bone marrow-derived dendritic cells of GFP-cGAS knock-In mice (INSERM U932, Institut Curie)

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