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Accession: PRJNA515714 ID: 515714

Genome binding/occupancy profiling of Smad4 in Th17 cells cultured at 37°C and 39.5°C after 24 hours. (house mouse)

See Genome Information for Mus musculus
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This project is a component of the ChIP-Seq of Smad4 in Th17 cells cultured at 37°C and 39.5°C and RNA-Seq of wild type and Smad4-deficient Th17 cells cultured at 37°C and 39.5°C
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1 additional project is a component of the ChIP-Seq of Smad4 in Th17 cells cultured at 37°C and 39.5°C and RNA-Seq of wild type and Smad4-deficient Th17 cells cultured at 37°C and 39.5°C.
47588 additional projects are related by organism.
Smad4 was required for febrile temperature enhanced Th17 differentiation. In order to further understand the mechanisms whereby Smad4 enhance Th17 differentiation, we conducted ChIP-seq analysis of Smad4 in Th17 cells cutured 37°C and 39. More...
AccessionPRJNA515714; GEO: GSE125263
Data TypeEpigenomics
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsWang X et al., "Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells.", Immunity, 2020 Feb 18;52(2):328-341.e5
SubmissionRegistration date: 17-Jan-2019
Dongchen's lab, Institute for Immunology and School of Medicine, Tsinghua University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes798
SRA Data Details
ParameterValue
Data volume, Gbases5
Data volume, Mbytes3127

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