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Genome Information for Homo sapiens
The study aim is to evaluate to what extent imipramine treatment of HCT-116 colorectal cell lines does affect fascin1-related or cytoskeleton-associated functions
Overall design: Gene expression signatures of HCT-116 cells treated with 20 µM imipramine and treated with 0.1% DMSO as control treatment were compared
| Accession | PRJNA515465; GEO: GSE125169 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Alburquerque-González B et al., "New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells.", Exp Mol Med, 2020 Feb;52(2):281-292 |
| Submission | Registration date: 16-Jan-2019 Hospital Clinico Universitario Virgen de la Arrixaca |
| Relevance | Medical |
Project Data:
| Resource Name | Number of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 125952 |
| Data volume, Processed Mbytes | 2 |
| Data volume, Supplementary Mbytes | 12 |