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Accession: PRJNA515293 ID: 515293

RNA seq analysis of primary human macrophages exposed to atheroma plaques homogenates with or without the Liver X receptor (LXR) antagonist GSK 2033 (human)

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To identify potential LXR target genes induced in the context of atherosclerosis we performed a transcriptomic analysis of human macrophages exposed or not to human carotid plaque homogenates in the presence or the absence of the LXR antagonist GSK 2033. More...
AccessionPRJNA515293; GEO: GSE125126
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMénégaut L et al., "Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages.", Cell Rep, 2020 May 19;31(7):107665
SubmissionRegistration date: 15-Jan-2019
Lipness, UMRS1231, INSERM
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes40
SRA Data Details
ParameterValue
Data volume, Gbases151
Data volume, Mbytes62889

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