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Accession: PRJNA515289 ID: 515289

DDX3 depletion represses translation of mRNAs with complex 5′ UTRs (human)

See Genome Information for Homo sapiens
We describe the subset of transcripts that require DDX3 for efficient translation. Overall design: Ribosome profiling upon DDX3 knockdown and DDX3 PAR-CLIP was performed from HEK 293 cells.
AccessionPRJNA515289; GEO: GSE125114
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsCalviello L et al., "DDX3 depletion represses translation of mRNAs with complex 5' UTRs.", Nucleic Acids Res, 2021 May 21;49(9):5336-5350
SubmissionRegistration date: 15-Jan-2019
RNA Biology and Posttranscriptional Regulation, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes837
SRA Data Details
ParameterValue
Data volume, Gbases49
Data volume, Mbytes17978

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