Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA515032 ID: 515032

Biomarkers of Vaccine Immunosafety (BioVacSafe)

BioVacSafe is a consortium of vaccine manufacturers together with academic, public, and SME participants, organized into focused workpackages to generate and disseminate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre- development to post-marketing surveillance. It aims to develop predictive biomarkers, models of inflammation and autoimmunity, and clinical events classification through a series of clinical trials and population-based studies with parallel pre-clinical models. The consortium has capability in transcriptomics, genotyping, proteomics, metabolomics and data mining, with depth and capacity to discover, validate and distribute novel biomarkers. More...
AccessionPRJNA515032
TypeUmbrella project
Grants
  • "Innovative Medicines Initiative Joint Undertaking" (Grant ID 115308, Innovative Medicines Initiative)
SubmissionRegistration date: 14-Jan-2019
BIOVACSAFE
- Ghent University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments2303
Publications
PubMed2
PMC2
Other datasets
BioSample2303
GEO DataSets4
GEO Data Details
ParameterValue
Data volume, Spots183151195
Data volume, Processed Mbytes4248
Data volume, Supplementary Mbytes39033
SRA Data Details
ParameterValue
Data volume, Gbases818
Data volume, Tbytes0.40
This project encompasses the following 7 sub-projects:
Project TypeNumber of Projects
Genome sequencing
Highest level of assembly :
SRA or Trace

3
BioProject
accession
Assembly
level
NameTitle
PRJNA492827 SRA or TraceBiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305ABiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305A (BIOVACSAFE)
PRJNA492829 SRA or TraceBiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305BBiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305B (BIOVACSAFE)
PRJNA492965 SRA or TraceBiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305CBiomarkers of Vaccine Immunosafety (BioVacSafe) - Study CRC305C (BIOVACSAFE)
Transcriptome or Gene expression4
BioProject
accession
OrganismTitle
PRJNA513089Homo sapiensGene expression signatures after immunisation with a range of live, inactivated and adjuvanted vaccines (BIOVACSAFE protocols 305A, 305B and 305C) (ICRF, Imperial College London)
PRJNA513088Homo sapiensGene expression signatures after immunisation with MF59C adjuvanted trivalent inactivated influenza vaccine for season 2014-2015 Northern hemisphere (BIOVACSAFE protocol 305D) (ICRF, Imperial College London)
PRJNA513261Homo sapiensGene expression signatures in blood and muscle biopsy after intramuscular immunization of healthy adult humans with adjuvanted vaccines (BIOVACSAFE protocol 305E) (ICRF, Imperial College London)
PRJNA494386Mus musculusIdentification of Biomarkers of Vaccine Reactogenicity (Imperial College London)

Supplemental Content

Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    Support Center