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Genome Information for Rattus norvegicus
Every living cell releases extracellular vesicles (EVs) that are critical for cellular signaling and a wide range of biological functions.
More...Every living cell releases extracellular vesicles (EVs) that are critical for cellular signaling and a wide range of biological functions. The potential diagnostic and therapeutic applications of EVs are well recognized, and rapidly expanding. Here we demonstrate a novel method for programmable control of EVs release and their cargo using external electric fields. As a proof of principle, we use primary cultured rat astrocytes to demonstrate how the frequency of external electrical stimulation (ES) selectively modulates EVs release, surface proteins, and microRNA profiles. This method could have a broad impact in biological science and medical applications.
Less...| Accession | PRJNA514311 |
| Data Type | Raw sequence reads |
| Scope | Monoisolate |
| Organism | Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus |
| Grants | - "Astrocyte-derived extracellular vesicles: Epilepsy promoters, repressors and brain stimulation" (Grant ID MNP #17.16, Minnesota Partnership for Biotechnology and Medical Genomics.)
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| Submission | Registration date: 10-Jan-2019
University of Minnesota School of Medicine |
| Relevance | Medical |
| Locus Tag Prefix | EPR51 |
Project Data:
| Resource Name | Number
of Links |
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| BioSample | 1 |
No public data is linked to this project. Any recently released data that cites this project will be linked to it within a few days.