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Accession: PRJNA514046 ID: 514046

Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence

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Staphylococcus aureus is a significant cause of human infection. Here, we demonstrate that mutations in the transcriptional repressor of purine biosynthesis, purR, enhance the pathogenic potential of S. More...
AccessionPRJNA514046; GEO: GSE124869
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismStaphylococcus aureus[Taxonomy ID: 1280]
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus; Staphylococcus aureus
PublicationsGoncheva MI et al., "Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence.", Nat Commun, 2019 Feb 15;10(1):775
SubmissionRegistration date: 9-Jan-2019
Heinrichs lab, Microbiology and Immunology, The University of Western Ontario
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Publications
PubMed1
PMC1
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases1
Data volume, Mbytes486

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