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7 additional projects are components of the Phase Separation of Ligand-Activated Enhancers Licenses Cooperative Chromosomal Enhancer Assembly.
Acutely activated enhancer in response to cell signaling regulate transcription by assembling phase separated ribonucleoprotein complex composed of transcription factors with disordered domains and RNA
Overall design: GROseq experiments was performed to examine the active transcription units and their response to different lenghts of estrogen treatment and 1,6-hexanediol
| Accession | PRJNA513872; GEO: GSE124826 |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Nair SJ et al., "Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly.", Nat Struct Mol Biol, 2019 Mar;26(3):193-203 |
| Submission | Registration date: 8-Jan-2019
UCSD |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 3 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 3 |
| GEO DataSets | 1 |