Durable Response of Enzalutamide-resistant Prostat... (ID 513162) - BioProject

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Accession: PRJNA513162 ID: 513162

Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts (human)

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The study aims to determine SPT effect on the CRPC growth and molecular alterations using LuCaP PDX CRPC models. More...

Accession	PRJNA513162; GEO: GSE124704
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Lam HM et al., "Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts.", Eur Urol, 2020 Feb;77(2):144-155
Submission	Registration date: 6-Jan-2019 Peter Nelson, Human Biology, Fred Hutchinson Cancer Research Center
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	48

Parameter	Value
Data volume, Gbases	247
Data volume, Tbytes	0.10

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