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Accession: PRJNA477840 ID: 477840

Gene expression analysis of Trem1-deficient Kupffer cells subjected to carbon tetracloride (CCl4) in liver fibrogenesis. (house mouse)

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Analysis of Kupffer cells at gene expression level. The hypothesis tested in the present study was that the expression of TREM-1 on Kupffer cells isolated from wild type mice subjected to single dose of carbon tetracloride and sacrificed 12 hours after injection influences the expression of multiple genes implicating in several signaling pathways. More...
AccessionPRJNA477840; GEO: GSE116236
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsNguyen-Lefebvre AT et al., "The innate immune receptor TREM-1 promotes liver injury and fibrosis.", J Clin Invest, 2018 Nov 1;128(11):4870-4883
SubmissionRegistration date: 25-Jun-2018
georgia cancer center
RelevanceModel Organism
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Sequence data
SRA Experiments60
Publications
PubMed1
PMC1
Other datasets
BioSample60
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases9
Data volume, Mbytes4295

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