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Accession: PRJNA477822 ID: 477822

DNA Methylation Potential Energy Landscape Analysis of Pediatric Pre-B cell Acute Lymphoblastic Leukemia (ALL) and Normal B cells and precursors (human)

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Acute lymphoblastic leukemia (ALL) is the most common cancer in children. We applied WGBS and the informME analysis pipeline to investigate the role of DNA methylation stochasticity in pre-B cell ALL. More...
AccessionPRJNA477822; GEO: GSE116229
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsKoldobskiy MA et al., "Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis.", Nat Biomed Eng, 2021 Apr;5(4):360-376
SubmissionRegistration date: 25-Jun-2018
Rangos 571, Center for Epigenetics, Johns Hopkins University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments51
Publications
PubMed1
PMC1
Other datasets
BioSample53
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes62981
SRA Data Details
ParameterValue
Data volume, Gbases2,265
Data volume, Tbytes0.91

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