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Accession: PRJNA477814 ID: 477814

Colonic single epithelial cell census reveals goblet cell drivers of barrier breakdown in inflammatory bowel disease (human)

See Genome Information for Homo sapiens
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66644 additional projects are related by organism.
We report the results of 3 single cell RNA-sequencing (10x, chromium) experiments looking to characterise the composition of the intestinal epithelial cells in health and Ulcerative Colitis in order to identify drivers of intestinal inflammation at the molecular level. More...
AccessionPRJNA477814; GEO: GSE116222
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsParikh K et al., "Colonic epithelial cell diversity in health and inflammatory bowel disease.", Nature, 2019 Mar;567(7746):49-55
SubmissionRegistration date: 25-Jun-2018
The MRC Weatherall Institute of Molecular Medicine, University of Oxford
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes177
SRA Data Details
ParameterValue
Data volume, Gbases306
Data volume, Mbytes65759

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