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Accession: PRJNA477602 ID: 477602

BCL-XL strikingly increases survival of human iPSCs after electroporation leading to highly efficient genome editing

Our study reports that transient delivery of BCL-XL increases survival of human induced pluripotent stem cells (iPSCs) by ~10-fold after plasmid transfection, leading to a 20- to 100-fold increase in HDR (homology directed repair) mediated knockin efficiency and a 5-fold increase in knockout efficiency. More...
AccessionPRJNA477602
Data TypeRaw sequence reads
ScopeMultispecies
SubmissionRegistration date: 23-Jun-2018
State Key Laboratory of Experimental Hematology, Chinese Academy of Medical Sciences
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Other datasets
BioSample21
SRA Data Details
ParameterValue
Data volume, Gbases163
Data volume, Mbytes69330

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