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Accession: PRJNA477510 ID: 477510

RNA-seq profiling of patient-derived xenograft models in Urothelial Cancer

To probe the tissue source (cancer cell VS stromal cell) of gene expression in the mixed tumor samples, we took advantage of a set of Urothelial Cancer patient-derived xenograft (PDX) models given that the transcriptome in these models is a mixture of human RNA (derived from cancer cells) and mouse RNA (derived from stromal cells). More...
AccessionPRJNA477510; GEO: GSE116159
Data TypeTranscriptome or Gene expression
ScopeMultispecies
PublicationsWang L et al., "EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer.", Nat Commun, 2018 Aug 29;9(1):3503
SubmissionRegistration date: 22-Jun-2018
Icahn school of medicine at Mount Sinai
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments15
Publications
PubMed1
PMC1
Other datasets
BioSample15
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes10
SRA Data Details
ParameterValue
Data volume, Gbases48
Data volume, Mbytes35039

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