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Genome Information for Homo sapiens
Transcriptomic changes in U2OS cells upon depletion of the RNA-binding protein ZNF598 were analyzed in non-treated and IL-1 beta treated cells in comparison to control U2OS cells
Overall design: U2OS cells transfected with a mis-match Control siRNA or ZNF598-specific siRNA were either left non-stimulated (ns) or were treated for 1h with 2ng/ml (final) IL-1 beta, transcriptomic changes were assessed by total RNASeq, biological duplicates of all conditions were measured
| Accession | PRJNA477345; GEO: GSE116126 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Tollenaere MAX et al., "GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling.", Cell Rep, 2019 Mar 26;26(13):3511-3521.e4 |
| Submission | Registration date: 21-Jun-2018
Simon Bekker-Jensen, Department of Molecular and Cellular Medicine (ICMM), University of Copenhagen |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 8 |
| Publications |
| PubMed | 1 |
| Other datasets |
| BioSample | 8 |
| GEO DataSets | 1 |