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Accession: PRJNA477344 ID: 477344

Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs (human)

See Genome Information for Homo sapiens
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We used human iPSC-CMs generated from healthy individuals and performed RNA-sequencing after 7 days of trastuzumab treatment to examine the mechanism associated with contraction dysfunction in iPSC-CMs after trastuzumab treatment. More...
AccessionPRJNA477344; GEO: GSE116127
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsKitani T et al., "Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer.", Circulation, 2019 May 21;139(21):2451-2465
SubmissionRegistration date: 21-Jun-2018
Stanford's Postdoctoral Scholar programs
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Publications
PubMed1
PMC1
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes10
SRA Data Details
ParameterValue
Data volume, Gbases49
Data volume, Mbytes18786

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