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Accession: PRJNA477225 ID: 477225

Sumoylation of RORgt controls TH17 differentiation and thymocyte development

Here we reveal sumoylation as a novel mechanism to regulate RORgt function. Loss of Sumo3, but not Sumo1, dampens TH17 differentiation and delays the progression of thymic immature CD8+ cells (ISP), both of which are dependent on RORgt. More...
AccessionPRJNA477225
Data TypeRaw sequence reads
ScopeMultispecies
SubmissionRegistration date: 20-Jun-2018
Beckman Research Institute of City of Hope
RelevanceMedical
Locus Tag PrefixDPQ58
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Other datasets
BioSample4
SRA Data Details
ParameterValue
Data volume, Gbases45
Data volume, Mbytes16885

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