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Genome Information for Rattus norvegicus
mRNA and miRNA expression profiling shows that the T3 supplementation reverted the expression of 87 genes and 11 miRNAs that were dysregulated in the untreated group
Overall design: A rat model of myocardial IR, with or without an early short-term T3-replacement, was used to predict putative T3-dependent miRNA-gene interactions targeted to mitochondria quality control and wound healing repair. One Sham, two IR, and two IRT3 rats were collected for mirna profiling.
| Accession | PRJNA476918; GEO: GSE116046 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus |
| Publications | Forini F et al., "Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion.", Sci Rep, 2018 Sep 14;8(1):13870 |
| Submission | Registration date: 20-Jun-2018 IIT, CNR |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 5 |
| GEO DataSets | 1 |