Sign in to NCBI

Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA476612 ID: 476612

Chemical inhibition of the Mycobacterium tuberculosis DosRST two-component regulatory system by targeting sensor kinase heme and response regulator DNA binding

See Genome Information for Mycobacterium tuberculosis
Navigate Across
3033 additional projects are related by organism.
The purpose of this study was to characterize the mechanism of action of the small molecules HC104 and HC106 Overall design: Mtb strain CDC1551 or the DosR mutant was grown at 37ºC in T-25 vented, standing tissue culture flasks in 8 mL of buffered 7H9 medium to an OD600 of 0. More...
AccessionPRJNA476612; GEO: GSE115892
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMycobacterium tuberculosis[Taxonomy ID: 1773]
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis
PublicationsZheng H et al., "Inhibiting Mycobacterium tuberculosis DosRST Signaling by Targeting Response Regulator DNA Binding and Sensor Kinase Heme.", ACS Chem Biol, 2020 Jan 17;15(1):52-62
SubmissionRegistration date: 15-Jun-2018
Microbiology and Molecular Genetics, Michigan State University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3
SRA Data Details
ParameterValue
Data volume, Gbases18
Data volume, Mbytes10131

Supplemental Content

Related information

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI
Support Center