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Accession: PRJNA476373 ID: 476373

Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] (human)

See Genome Information for Homo sapiens
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This project is a component of the Dynamic 3D chromosomal landscapes in acute leukemia
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5 additional projects are components of the Dynamic 3D chromosomal landscapes in acute leukemia.
66643 additional projects are related by organism.
Gro-seq analysis following NOTCH1 inhibition and release gave an ovierview of the kinetics of NOTCH1 dependent transcriptional regulatiion Overall design: NOTCH1-driven T-ALL cell line CUTLL1 was treated with gamma-secretase inhibitor (gSI) for 72 hours. More...
AccessionPRJNA476373; GEO: GSE115894
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsKloetgen A et al., "Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia.", Nat Genet, 2020 Apr;52(4):388-400
SubmissionRegistration date: 15-Jun-2018
Department of Pathology, NYU School of Medicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Publications
PubMed1
PMC1
Other datasets
BioSample20
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1166
SRA Data Details
ParameterValue
Data volume, Gbases19
Data volume, Mbytes6621

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