Gene expression analysis of human bronchial airway... (ID 476231) - BioProject

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Accession: PRJNA476231 ID: 476231

Gene expression analysis of human bronchial airway epithelial BEAS-2B cells stimulated by glucocorticoid, long-acting β2-adrenoceptor agonist or both combined. (human)

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In asthma, the clinical efficacy of inhaled corticosteroids (ICSs) is enhanced by long-acting β2-adrenoceptor agonists (LABAs). More...

Accession	PRJNA476231; GEO: GSE115830
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications (total 3) Less...	Mostafa MM et al., "Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting β ₂-Adrenoceptor Agonist Combination Therapy in Asthma.", Mol Pharmacol, 2021 Mar;99(3):197-216 More... Mostafa MM et al., "Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting β ₂-Adrenoceptor Agonist Combination Therapy in Asthma.", Mol Pharmacol, 2021 Mar;99(3):197-216 Mostafa MM et al., "Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells.", BMC Med Genomics, 2019 Jan 31;12(1):29 Rider CF et al., "Long-Acting β₂-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.", Mol Pharmacol, 2018 Sep;94(3):1031-1046 Less...
Submission	Registration date: 15-Jun-2018 Airway Inflammation Research Group, Snyder Institute for Chronic Diseases, University of Calgary
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Spots	3161280
Data volume, Processed Mbytes	65
Data volume, Supplementary Mbytes	141

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Gene expression analysis of human bronchial airway epithelial BEAS-2B cells stim...
Gene expression analysis of human bronchial airway epithelial BEAS-2B cells stimulated by glucocorticoid, long-acting β2-adrenoceptor agonist or both combined.
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