We report transcriptional and genome-wide DNA methylation analyses at single base resolution of 5-methyl-, 5-hydroxymethyl-, and 5-formyl/carboxy-cytosine during the differentiation of human induced pluripotent stem cells along the neural trajectory in normal and Alzheimer's disease.
| Accession | PRJNA476128 |
| Data Type | Raw sequence reads |
| Scope | Multispecies |
| Publications | Fetahu IS et al., "Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.", Sci Adv, 2019 Aug;5(8):eaaw2880 |
| Grants | - "Epigenetic Mechanisms of Alzheimer’s Disease: Focusing on Regulation of DNA and Histone Methylation" (Grant ID A220159, Biogen Idec)
|
| Submission | Registration date: 14-Jun-2018
Brigham and Women's Hospital |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 45 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 15 |