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Accession: PRJNA476065 ID: 476065

Gene expression analysis of a MLL-rearranged leukaemia cell line, PER-485, treated with small molecule CCI-006. (human)

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This project is a component of the Analysis of changes in gene expression upon CCI-006 treatment and resistance development of the MLL-rearranged leukaemia cell line PER-485
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1 additional project is a component of the Analysis of changes in gene expression upon CCI-006 treatment and resistance development of the MLL-rearranged leukaemia cell line PER-485.
66643 additional projects are related by organism.
A phenotypic cell-based high-throughput screen identified a novel small molecule, CCI-006 with selective cytotoxic activity against MLL-rearranged leukaemia cell lines. More...
AccessionPRJNA476065; GEO: GSE115793
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsSomers K et al., "A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.", Oncogene, 2019 May;38(20):3824-3842
SubmissionRegistration date: 14-Jun-2018
Children's Cancer Institute, Lowy Cancer Research Centre, UNSW
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots283938
Data volume, Processed Mbytes10
Data volume, Supplementary Mbytes15

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