BioProject

We propose to conduct whole genome sequencing of 100 diverse Vibrio cholerae isolates including pathogenic and nonpathogenic strains belonging to O1, O139 and non-O1/O139 serogroups to understand the evolution of this important pathogen. More...

We propose to conduct whole genome sequencing of 100 diverse Vibrio cholerae isolates including pathogenic and nonpathogenic strains belonging to O1, O139 and non-O1/O139 serogroups to understand the evolution of this important pathogen. Toxigenic V. cholerae normally exists in an aquatic ecosystem, but infects humans to cause devastating epidemics of cholera that causes 120,000 deaths and about 3.5 million cases worldwide every year. We seek to analyze strains isolated from both cholera patients and the aquatic environment in Bangladesh, where seasonal epidemics of cholera occur every year.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ Less...