Iron is an essential nutrient for infants and gut bacteria alike. Iron supplementation and/or fortification to anemic infants have led to an underrepresentation of important commensals e.
More...Iron is an essential nutrient for infants and gut bacteria alike. Iron supplementation and/or fortification to anemic infants have led to an underrepresentation of important commensals e.g. bifidobacteria and lactobacilli and overrepresentation of enteropathogens.
In healthy, non-anemic infants, administration of iron as drops, even in a dose comparable to the daily iron requirement and for a short time, leads to a decreased relative abundance of lactobacilli and potentially increases susceptibility to bacterial infection.
Even a low dose of iron administered as drops may have unwarranted effects on the composition of gut microbiota. This calls for caution regarding iron supplementation of healthy, non-anemic infants. Providing pre- or probiotics may alleviate this issue. Less...
| Accession | PRJNA475589 |
| Data Type | Raw sequence reads, Targeted Locus (Loci) |
| Scope | Multispecies |
| Submission | Registration date: 11-Jun-2018
Swedish Defense Research Agancy |
| Relevance | Medical |
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