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Accession: PRJNA475569 ID: 475569

SWI/SNF Chromatin Remodeling Factor BRG1 is Synthetic Required for PTEN-deficient Prostate Cancer

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA475569; GEO: GSE115619
TypeUmbrella project
PublicationsDing Y et al., "Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer.", J Clin Invest, 2019 Feb 1;129(2):759-773
SubmissionRegistration date: 11-Jun-2018
Laboratory of Tumor Progression and Metastasis, Institute of Health Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
PMC1
Other datasets
BioSample9
GEO DataSets4
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes767
SRA Data Details
ParameterValue
Data volume, Gbases27
Data volume, Mbytes9771
SWI/SNF Chromatin Remodeling Factor BRG1 is Synthetic Required for PTEN-deficient Prostate Cancer encompasses the following 3 sub-projects:
Project TypeNumber of Projects
Epigenomics2
BioProject
accession
OrganismTitle
PRJNA475576Homo sapiensCompare chromatin open regions (OCRs) between PTEN-KD and PTEN/BRG1-KD 22RV-1 cells by ATAC-Seq (Laboratory of Tumor Progression...)
PRJNA475577Homo sapiensBRG1 occupancy profiling by high throughput sequencing from control and PTEN knockdown 22RV-1 cells (Laboratory of Tumor Progression...)
Transcriptome or Gene expression1
BioProject
accession
OrganismTitle
PRJNA475578Homo sapiensTranscriptome analysis of control and BRG1-depleted 22RV-1 cells with or without PTEN ablation (Laboratory of Tumor Progression...)

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