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Accession: PRJNA475566 ID: 475566

Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds (human)

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This project is a component of the Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa(WT) and ERa(MUT) breast cancer.
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3 additional projects are components of the Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa(WT) and ERa(MUT) breast cancer..
66643 additional projects are related by organism.
The objective of this experiment was to compare the affect of H3B-5942 treatment on global gene expression and to compare to treatment with standard of care agents tamoxifen and fulvestrant. More...
AccessionPRJNA475566; GEO: GSE115609
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 11-Jun-2018
H3 Biomedicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes6
SRA Data Details
ParameterValue
Data volume, Gbases129
Data volume, Mbytes48574

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