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Accession: PRJNA475564 ID: 475564

ChIP-Seq analysis of estrogen deprived MCF7 cells treated with H3B-5942 and standards of care compounds (human)

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This project is a component of the Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa(WT) and ERa(MUT) breast cancer.
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3 additional projects are components of the Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa(WT) and ERa(MUT) breast cancer..
66644 additional projects are related by organism.
The goal of this experiment was to interrogate the potential transcriptional impact of H3B-5942 by investigating its influence on genome-wide DNA-binding modes of ERa in MCF7 cells using chromatin immunoprecipitation followed by high-throughput DNA sequencing (ChIP-Seq). More...
AccessionPRJNA475564; GEO: GSE115607
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 11-Jun-2018
H3 Biomedicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments11
Other datasets
BioSample11
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2121
SRA Data Details
ParameterValue
Data volume, Gbases27
Data volume, Mbytes10025

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