See
Genome Information for Mus musculus
Using a novel immunocompetent quadruple (PtenF/F; Trp53F/F; Rb1F/F;Rbl1-/-) knockout transgenic mouse model of highly aggressive metastatic muscle-invasive BC, we demonstrate that treatment with CM272 and CDDP results in a significant tumor and metastasis regression with a very significant prolonged survival
Overall design: Gene expression was compared between normal bladders from transgenic CKO mice (Rbf/f, Ptenf/f, Tp53f/f, p107-/- ), tumor bladders from CKO inoculated with Adeno-Cre in the bladder, bladders from CKO treated with CM272+CDDP, and metastasis from these mice.
| Accession | PRJNA475147; GEO: GSE115485 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Submission | Registration date: 7-Jun-2018
CIEMAT |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 1319120 |
| Data volume, Processed Mbytes | 38 |
| Data volume, Supplementary Mbytes | 414 |