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Accession: PRJNA475064 ID: 475064

Expression and transcript isoform profiling of reprogramming cells expressing a Sox2 mutant lacking a putative RNA binding motif [RNA-Seq] (house mouse)

See Genome Information for Mus musculus
Total RNA was extracted at different stages of somatic cell reprogramming of OG2-MEFs to induced pluripotent stem cells to analyse the effect of a Sox2 mutant lacking a putative RNA binding motif on genes expression and post-transcriptional processing Overall design: Expression profiling by high throughput sequencing of reprogramming cells.
AccessionPRJNA475064; GEO: GSE115451
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsHou L et al., "Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2.", Nucleic Acids Res, 2020 Apr 17;48(7):3869-3887
SubmissionRegistration date: 7-Jun-2018
Miguel, South China Institute for Stem Cell Biology and Regenerative Medicine Key Laboratory of Regenerative Biology, CAS, Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments18
Publications
PubMed1
PMC1
Other datasets
BioSample18
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes24
SRA Data Details
ParameterValue
Data volume, Gbases128
Data volume, Mbytes48287

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