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Accession: PRJNA474756 ID: 474756

RNA-Seq analysis of HIF-2a-responsive genes in clear-cell renal cell carcinoma (human)

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We performed RNA-Seq analysis of wildtype and three EPAS1-/- 786-O single cell clones generated by CRISPR/Cas9 to identify the HIF-2a-responsive genes in this cell line. More...
AccessionPRJNA474756; GEO: GSE115389
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsZou Y et al., "A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.", Nat Commun, 2019 Apr 8;10(1):1617
SubmissionRegistration date: 5-Jun-2018
Chemical Biology and Therapeutic Sciences, Broad Institute of MIT and Harvard
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments7
Publications
PubMed1
PMC1
Other datasets
BioSample7
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases95
Data volume, Mbytes40234

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