Displacement of WDR5 from chromatin by a pharmacol... (ID 474736) - BioProject

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Accession: PRJNA474736 ID: 474736

Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity (human)

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We discovered potent small molecule inhibitors against the WIN site of WDR5. More...

Accession	PRJNA474736; GEO: GSE115377
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Bryan AF et al., "WDR5 is a conserved regulator of protein synthesis gene expression.", Nucleic Acids Res, 2020 Apr 6;48(6):2924-2941 Aho ER et al., "Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.", Cell Rep, 2019 Mar 12;26(11):2916-2928.e13
Submission	Registration date: 5-Jun-2018 Vanderbilt University Medical Center
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	6

Parameter	Value
Data volume, Gbases	872
Data volume, Tbytes	0.36

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Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with...
Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity
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