BioProject

Transcriptional profiling of human pulmonary artery endothelial (HAPEC) and smooth muscle (PASM) cells comparing control untreated cells with cells transfected with ARSB-siRNA. More...

Transcriptional profiling of human pulmonary artery endothelial (HAPEC) and smooth muscle (PASM) cells comparing control untreated cells with cells transfected with ARSB-siRNA. Goal was to determine the effects of silenced of arylsufatase B on global gene expression in HAPEC and PASM cells. Overall design: Two-condition experiment, non-transfected vs. ARSB-siRNA transfected cells. Biological replicates: 2 cell lines, 4 control replicates, 4 transfected replicates. Please note that the experiments were performed technically as dual channel (eg, Cy3 and Cy5-labeled samples hybridized to the same array) but the results were processed as they are single channel (Cy3 and Cy5 signals are calculated; total 8 raw data files for 16 sample records). Raw data file (associated with each sample) is indicated in the sample description field and is linked to the corresponding control sample records. Less...