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Accession: PRJNA474111 ID: 474111

Genome wide analysis of SAHA (vorinostat) treatment in human iPSC-derived neurons from Tau A152T patients and controls (human)

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This project is a component of the Identification of evolutionary conserved gene networks that mediate neurodegenerative dementia
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6 additional projects are components of the Identification of evolutionary conserved gene networks that mediate neurodegenerative dementia.
66643 additional projects are related by organism.
Purpose: The goal of this study was to assess gene expression changes upon SAHA treatment in neurons derived from patients with A152T Tau mutation Overall design: iPSC derived neurons were treated with SAHA at different dosage for several days
AccessionPRJNA474111; GEO: GSE115205
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsSwarup V et al., "Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.", Nat Med, 2019 Jan;25(1):152-164
SubmissionRegistration date: 1-Jun-2018
Neurobiology and Behavior, University of California Irvine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments36
Publications
PubMed1
PMC1
Other datasets
BioSample36
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes15
SRA Data Details
ParameterValue
Data volume, Gbases290
Data volume, Tbytes0.10

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