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Accession: PRJNA474015 ID: 474015

Gene expression analysis of wild type and Lats1/2-mutated uveal melanoma (house mouse)

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47588 additional projects are related by organism.
Lats1/2 kinases are the core Hippo pathway kinases. In this study, we use RNAseq to analyze the gene expression profiles of adult mouse uveal tract cells and mouse uveal melanoma generated by Lats1/2 deletion induced by AAV-based Cre injection into mouse uveal tract. More...
AccessionPRJNA474015; GEO: GSE115181
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLi H et al., "YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.", Cell Rep, 2019 Dec 3;29(10):3200-3211.e4
SubmissionRegistration date: 31-May-2018
Molecular Cellular and Cancer Biology, UMass Medical School
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments5
Publications
PubMed1
PMC1
Other datasets
BioSample5
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases9
Data volume, Mbytes5127

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