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2 additional projects are components of the Transmission of extracellular vesicle packaged lncRNA from TAMs to breast cancer cells.
We compared the lncRNA expression profile of MDMs and TAMs. TAMs were polarized by treating human monocytes-derived macrophages (MDMs) with the conditioned media of MDA-MB-231 cells.
Overall design: A six chip study using total RNA recovered from MDMs and TAMs from 3 donors.
| Accession | PRJNA473559; GEO: GSE115037 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Chen F et al., "Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells.", Nat Cell Biol, 2019 Apr;21(4):498-510 |
| Submission | Registration date: 29-May-2018
sun yat-sen university |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 725592 |
| Data volume, Processed Mbytes | 25 |
| Data volume, Supplementary Mbytes | 129 |