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Accession: PRJNA473524 ID: 473524

Whole exome sequencing analyzed the off-target effect of gene editing through BE3 system. (house mouse)

See Genome Information for Mus musculus
We used the whole exome sequencing to analyze the off-target effect of base editing system in mouse genomic DNA, which was extracted from haploid stem cells, mouse tails of semi-cloned embryos and mutant pups. More...
AccessionPRJNA473524; GEO: GSE115017
Data TypeVariation
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLi Q et al., "CRISPR-Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development.", Nat Cell Biol, 2018 Nov;20(11):1315-1325
SubmissionRegistration date: 29-May-2018
Jinsong Li Lab, institute of biochemistry and cell biology, Chinese Academy of Science
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments14
Publications
PubMed1
Other datasets
BioSample14
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes60
SRA Data Details
ParameterValue
Data volume, Gbases252
Data volume, Mbytes81309

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